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MYASTHENIA GRAVIS EVALUATION W/ MUSK REFLEX, SERUM
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
Test Code
MGMR
Alias/See Also
MUSK MYASTHENIA, MYASTHENIA GRAVIS ANTIBODIES, THYMOMA
CPT Codes
83519
Preferred Specimen
3 ML SERUM FROM A RED TOP TUBE
Minimum Volume
2 mL
Instructions
1. Patient should have no general anesthetic or muscle-relaxant drugs in the preceding 24 hours.
2. For optimal antibody detection, specimen collection is recommended prior to initiation of immunosuppressant medication.
3. This test should not be requested in patients who have recently received radioisotopes, therapeutically or diagnostically, because of potential assay interference. The specific waiting period before specimen collection will depend on the isotope administered, the dose given, and the clearance rate in the individual patient. Specimens will be screened for radioactivity prior to analysis. Radioactive specimens received in the laboratory will be held 1 week and assayed if sufficiently decayed, or canceled if radioactivity remains.
2. For optimal antibody detection, specimen collection is recommended prior to initiation of immunosuppressant medication.
3. This test should not be requested in patients who have recently received radioisotopes, therapeutically or diagnostically, because of potential assay interference. The specific waiting period before specimen collection will depend on the isotope administered, the dose given, and the clearance rate in the individual patient. Specimens will be screened for radioactivity prior to analysis. Radioactive specimens received in the laboratory will be held 1 week and assayed if sufficiently decayed, or canceled if radioactivity remains.
Transport Container
PLASTIC POUR OFF TUBE
Transport Temperature
REFRIGERATED
Specimen Stability
Room Temperature: 72 HOURS
Refrigerated: 28 DAYS
Frozen: 28 DAYS
Refrigerated: 28 DAYS
Frozen: 28 DAYS
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
GROSS HEMOLYSIS, GROSS ICTERUS, GROSS LIPEMIA
Methodology
RIA, FLOW CYTOMETRY
Setup Schedule
MONDAY-FRIDAY
Report Available
3-11 DAYS
Clinical Significance
Diagnosis for autoimmune myasthenia gravis (MG) in adults and children Distinguishing autoimmune from congenital MG in adults and children or other acquired forms of neuromuscular junction transmission disorders Establishing a quantitative baseline value that allows comparison with future levels if weakness is worsening
Performing Laboratory
Mayo Clinic Laboratories Rochester Main Campus
200 First Street SW
Rochester, MN 55905
