Antigliadin Antibody Panel [8889]

For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.

GLIAG

8889

Includes: Antigliadin IgA Antibody(74221), Antigliadin IgG Antibody(74222)

1 mL serum (minimum 0.5 mL) 

SST or Red top: Avoid hemolysis. Invert a minimum of 5 times, then allow to clot in an upright position for 30 minutes. Centrifuge the the tube for at least 10 minutes. Keep tightly stoppered.

SST (speckled top), Red top , Plastic Vial (transfer) tube

Refrigerated (preferred)
 

Room Temperature = n/a
Refrigerated = 5 days
Frozen = at least 7 days

Even days of the week
BS

3 days

Antigliadin antibody (AGA) is present in the serum of patients with hypersensitivity to gluten in the diet (wheat). The antibody titers are reduced or disappear when the patient is on a gluten-free diet. Gluten-induced gastrointestinal dysfunction is called Celiac Disease. There are two types of antibodies, IgA and IgG. IgA antibody is specific and IgG antibody is a sensitive marker to Celiac Disease. Measurement of the combined antibodies provides a specificity of 84% and a sensitivity of 94% for diagnosis of Celiac Disease. Other conditions associated with increased AGA are dermatitis herpetoformis (25% of patients), and (rarely) gastrointestinal and/or autoimmune disease.Determination of antigliadin antibody is useful in the management of patients with Celiac Disease, managed with a gluten-free diet.