Aldosterone/Plasma Renin Activity Ratio, LC/MS/MS

Message

For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.

Test Code

ARENIN

Alias/See Also

16845

CPT Codes
82088, 84244

Includes

Aldosterone, LC/MS and Plasma Renin Activity, LC/MS/MS

Preferred Specimen

1.8 mL Frozen Plasma collected in a EDTA (lavender-top) tube

Minimum Volume

0.8 mL

Instructions

Specimen cannot be shared, draw a separate tube for any other plasma testing. Collect a mid-morning blood sample after patient has been upright (sitting, standing, or walking) for a minimum of 2 hours, then have them sit 5-15 minutes prior to collection. Centrifuge lavender top, transfer plasma to a plastic vial and freeze.

Transport Container

Plastic screw-cap vial

Transport Temperature

Frozen

Specimen Stability

Room temperature: 24 hours
Refrigerated: 24 hours
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Moderate to gross hemolysis; plasma collected in plasma separator tube; received thawed

Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Monday - Saturday

Report Available

4 - 6 days

Clinical Significance

The Aldosterone-renin ratio is used to screen for primary aldosteronism.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Dr
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.