Prolactin, Total and Monomeric

Test Code

TMPROL

Alias/See Also

16122

CPT Codes
84146 (x2)

Includes

Prolactin, Total
Prolactin, Monomeric

Preferred Specimen

1 mL serum

Patient Preparation
Fasting specimen is recommended but not required

Minimum Volume

0.4 mL

Instructions

Collect blood by venipuncture into plain tubes (without anticoagulant). Separate the serum from the cells.

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 7 days
Frozen: 6 months

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis • Plasma

Methodology
Immunoassay (IA) • PEG Precipitation

Setup Schedule

Set up: Wed; Report Available: 2-9 days

Clinical Significance

For some patients the level of Prolactin measured by immunoassay may be inaccurate with respect to the level of monomeric, biologically active Prolactin. The Macroprolactin by PEG Precipitation test can help to identify if a patient sample has elevated Prolactin due to mostly inactive protein-bound Prolactin (Macroprolactin).

Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.