Human Anti-mouse Antibody (HAMA)

Test Code

HAMA

Alias/See Also

1468

CPT Codes
83520

Preferred Specimen

1 mL frozen serum collected in a red-top tube (no gel)

Minimum Volume

0.5 mL

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 24 hours
Frozen -20° C: 21 days
Frozen -70° C: 90 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross lipemia • Serum Separator Tube (SST)

Methodology
Enzyme Linked Immunosorbent Assay (ELISA)

Setup Schedule

Set up: Thurs; Report available: 7-14 days

Clinical Significance

The presence of Human Anti-mouse Antibody (HAMA) has been associated with patients receiving injections of Murine Monoclonal Antibody (MAB) for diagnostics and/or therapeutic purposes. HAMA produced in response to monoclonal antibody therapy may interfere with therapeutic efficacy. Therefore, it is recommended that baseline HAMA levels are determined prior to the initiation of therapy with murine-derived proteins.

Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.