Hemoglobin S & F Quantitation

Test Code
HGBSF


Preferred Specimen
6 mL EDTA whole blood


Minimum Volume
1 mL


Transport Container
Original collection vial


Transport Temperature
Refrigerated


Specimen Stability
Refrigerated 7days


Report Available
2-3 days


Reference Range
See report for normal ranges.


Clinical Significance
The treatment of red blood cell sickling disorders may involve many therapeutic modalities. Two of the most important and beneficial are treatment with hydroxyurea and chronic transfusion therapy. Hydroxyurea causes elevation of hemoglobin F (Hb F) levels, and transfusion serves to lower the percentage of hemoglobin S (Hb S). Both of these therapeutic modalities act to lessen the number and severity of sickling crises. Thus, periodic monitoring of Hb F and Hb S levels are needed to guide further therapy.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.