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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Hemoglobin S & F Quantitation
Test CodeHGBSF
Preferred Specimen
6 mL EDTA whole blood
Minimum Volume
1 mL
Transport Container
Original collection vial
Transport Temperature
Refrigerated
Specimen Stability
Refrigerated 7days
Report Available
2-3 days
Reference Range
See report for normal ranges.
Clinical Significance
The treatment of red blood cell sickling disorders may involve many therapeutic modalities. Two of the most important and beneficial are treatment with hydroxyurea and chronic transfusion therapy. Hydroxyurea causes elevation of hemoglobin F (Hb F) levels, and transfusion serves to lower the percentage of hemoglobin S (Hb S). Both of these therapeutic modalities act to lessen the number and severity of sickling crises. Thus, periodic monitoring of Hb F and Hb S levels are needed to guide further therapy.