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Lipid Panel, Standard
Message
Fasting is recommended.
Test Code
LIPID
Includes
Total Cholesterol, HDL Cholesterol, Triglycerides, LDL-Cholesterol, VLDL Cholesterol (calculated)
Preferred Specimen
1 mL serum
Patient Preparation
If a cholesterol or HDL cholesterol measurement is to be performed along with triglycerides, the patient should be fasting 9-12 hours prior to collection.
Minimum Volume
0.5 mL
Other Acceptable Specimens
Heparinized plasma
Instructions
None
Transport Container
Serum separator tube (SST)
Transport Temperature
Ambeint
Specimen Stability
Ambient: 7 days
Refrigerated: 7 days
Refrigerated: 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Moderate to gross icterus • Anticoagulants other than heparin
Methodology
Spectrophotometry (SP)
Setup Schedule
24/7
Report Available
Same day
Reference Range
See report
Clinical Significance
The Lipid Panel, Standard measures serum cholesterol and triglyceride (TG) levels; it includes evaluation of the cholesterol/HDL-C ratio (calculated), HDL-C, LDL-C (calculated), non-HDL-C (calculated), total cholesterol, and TG. Comprehensive lipid assessment aids in the evaluation of cardiovascular risk and the likelihood of suffering an ischemic event. It is also useful for the prevention and management of atherosclerotic disease, as well as the diagnosis of metabolic syndrome [1].
Cardiovascular disease (CVD) is the leading cause of death in the United States. The risk of developing CVD and having an ischemic event is significantly increased in individuals with high LDL-cholesterol (LDL-C) and TG levels [2,3]. The American Heart Association (AHA) recommends that Americans aged 20 and above have their lipid levels tested every 4 to 6 years. Children should have their cholesterol tested for the first time between ages 9 and 11, and again between ages 17 and 21. Testing should start earlier if there is family history of high cholesterol [4].
The AHA recommends repeat measurement of LDL-C within 4 to 12 weeks of starting or changing lipid-lowering therapy, to assess response and adherence, and then every 3 to 12 months as appropriate [4].
Treatment with N-acetyl cysteine (NAC) for acetaminophen overdose may generate a falsely low result for cholesterol. Venipuncture immediately after or during administration of the painkiller metamizole (dipyrone) may also lead to falsely low results for cholesterol.
Note: Any or all individual tests from a panel can be ordered separately.
References
1. Stone NJ, et al. Circulation. 2014;129(suppl 2):S1-S45.
2. CDC. Heart disease fact sheet. Reviewed August 23, 2017.
https://www.cdc.gov/dhdsp/data_statistics/fact_sheets/fs_heart_disease.htm
3. Arbel Y, et al. Card Diabetol. 2016;15:11.
4. AHA. Cholesterol management guide for healthcare practitioners. November 10, 2018.
https://www.heart.org/-/media/files/health-topics/cholesterol/chlstrmngmntgd_181110.pdf
Cardiovascular disease (CVD) is the leading cause of death in the United States. The risk of developing CVD and having an ischemic event is significantly increased in individuals with high LDL-cholesterol (LDL-C) and TG levels [2,3]. The American Heart Association (AHA) recommends that Americans aged 20 and above have their lipid levels tested every 4 to 6 years. Children should have their cholesterol tested for the first time between ages 9 and 11, and again between ages 17 and 21. Testing should start earlier if there is family history of high cholesterol [4].
The AHA recommends repeat measurement of LDL-C within 4 to 12 weeks of starting or changing lipid-lowering therapy, to assess response and adherence, and then every 3 to 12 months as appropriate [4].
Treatment with N-acetyl cysteine (NAC) for acetaminophen overdose may generate a falsely low result for cholesterol. Venipuncture immediately after or during administration of the painkiller metamizole (dipyrone) may also lead to falsely low results for cholesterol.
Note: Any or all individual tests from a panel can be ordered separately.
References
1. Stone NJ, et al. Circulation. 2014;129(suppl 2):S1-S45.
2. CDC. Heart disease fact sheet. Reviewed August 23, 2017.
https://www.cdc.gov/dhdsp/data_statistics/fact_sheets/fs_heart_disease.htm
3. Arbel Y, et al. Card Diabetol. 2016;15:11.
4. AHA. Cholesterol management guide for healthcare practitioners. November 10, 2018.
https://www.heart.org/-/media/files/health-topics/cholesterol/chlstrmngmntgd_181110.pdf
