Lipase

Test Code

LIP

Preferred Specimen

1 mL serum

Patient Preparation
The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been...determined to interfere with assays for...cholesterol, uric acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.

Minimum Volume

0.5 mL

Other Acceptable Specimens

Heparinized plasma

Instructions

Note: N-acetyl-p-benzoquinone imine (NAPQI) (metabolite of acetaminophen) will generate erroneously low results in samples for patients that have taken toxic doses of acetaminophen.

Transport Container

Serum separator tube (SST)

Transport Temperature

Ambeint

Specimen Stability

Ambient: 7 days
Refrigerated: 7 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Grossly icteric

Methodology
Spectrophotometry (SP)

Setup Schedule

24/7

Report Available

Same day

Reference Range

16-63 U/L

Clinical Significance

Confirmatory evidence for diagnosis of pancreatitis.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.