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Gamma Glutamyl Transferase (GGT)
Test CodeGGT
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Other Acceptable Specimens
Heparinized plasma
Transport Container
Serum separator tube (SST)
Transport Temperature
Ambient
Specimen Stability
Refrigerated: 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Plasma
Methodology
Spectrophotometry (SP)
Setup Schedule
24/7
Report Available
Same day
Reference Range
Males: 11-65 IU/L
Females: 11-43 IU/L
Females: 11-43 IU/L
Clinical Significance
Elevated GGT is found in all forms of liver disease. Measurement of GGT is used in the diagnosis and treatment of alcoholic cirrhosis, as well as primary and secondary liver tumors. It is more sensitive than alkaline phosphatase, the transaminases, and leucine aminopeptidase in detecting obstructive jaundice, cholangitis, and cholecystitis. Normal levels of GGT are seen in skeletal diseases; thus, GGT in serum can be used to ascertain whether a disease, suggested by elevated alkaline phosphatase, is skeletal or hepatobiliary.