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Gentamicin, Random
Test CodeGENR
Preferred Specimen
1 mL serum
Patient Preparation
Collect as a trough just before next dose. Collect peak at the end of a 60 minute IV infusion, 30 minutes after the end of a 30 minute IV infusion or 60 minutes after the IM dose.
Minimum Volume
0.2 mL
Other Acceptable Specimens
Heparinized plasma
Transport Container
Original collection vial
Transport Temperature
Refrigerated (cool packs)
Specimen Stability
Refrigerated: 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Anticoagulants other than heparin
Methodology
Immunoassay (IA)
Setup Schedule
24/7
Report Available
Same day
Reference Range
Reference ranges are not avaialbe when not drawn in relation to time dose is given.
Clinical Significance
Gentamicin is an aminoglycoside antibiotic used in the treatment of gram-positive and gram-negative bacterial infections, especially Pseudomonas, Proteus, Klebsiella and Staphylococcus. Gentamicin is potentially nephrotoxic and ototoxic. Serial monitoring of peak and trough serum levels may provide the clinician with information to maintain safe and therapeutic levels.