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Gentamicin, Peak
Test CodeGENP
Preferred Specimen
1 mL serum
Patient Preparation
Collect peak at end of 60 minute IV infusion, 30 minutes after end of 30 minutes IV infusion or 60 minutes after IM dose
Minimum Volume
0.2 mL
Other Acceptable Specimens
Heparinized plasma
Instructions
Collect post dose according to route specific timing guidlelines.
Transport Container
Original collection vial
Transport Temperature
Refrigerated (cool packs)
Specimen Stability
Refrigerated: 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Anticoagulants other than heparin.
Methodology
Immunoassay (IA)
Setup Schedule
24/7
Report Available
Same day
Reference Range
5.0-12.0 ug/dL
Clinical Significance
Gentamicin is an aminoglycoside antibiotic used in the treatment of gram-positive and gram-negative bacterial infections, especially Pseudomonas, Proteus, Klebsiella and Staphylococcus. Gentamicin is potentially nephrotoxic and ototoxic. Serial monitoring of peak and trough serum levels may provide the clinician with information to maintain safe and therapeutic levels.