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Gentamicin, Trough
Test CodeGENT
Preferred Specimen
1 mL serum
Patient Preparation
Collect as a trough just prior to next dose
Minimum Volume
0.2 mL
Other Acceptable Specimens
Heparinized plasma
Instructions
Collect just prior to next dose.
Transport Container
Original collection vial
Transport Temperature
Refrigerated (cool packs)
Specimen Stability
Refrigerated: 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Anticoagulants other than heparin
Methodology
Immunoassay (IA)
Setup Schedule
24/7
Report Available
Same day
Reference Range
0.0-2.0 ug/dL
Clinical Significance
Gentamicin is an aminoglycoside antibiotic used in the treatment of gram-positive and gram-negative bacterial infections, especially Pseudomonas, Proteus, Klebsiella and Staphylococcus. Gentamicin is potentially nephrotoxic and ototoxic. Serial monitoring of peak and trough serum levels may provide the clinician with information to maintain safe and therapeutic levels.
