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| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Theophylline
Test CodeTHEO
Preferred Specimen
1 mL serum
Patient Preparation
Collect as a trough just prior to next dose
Minimum Volume
0.2 mL
Other Acceptable Specimens
Heparinized plasma
Transport Container
Original collection vial
Transport Temperature
Refrigerated (cool packs)
Specimen Stability
Refrigerated: 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Anticoagulants other than heparin
Methodology
Immunoassay (IA)
Setup Schedule
24/7
Report Available
Same day
Reference Range
10-20 ug/mL
Toxic: >25 ug/mL
Toxic: >25 ug/mL
Clinical Significance
Theophylline is used in the treatment of bronchial asthma as well as in the treatment of chronic obstructive pulmonary disease and episodes of prolonged apnea in pre-term infants. Theophylline levels are monitored to assure adequate therapeutic levels are achieved and to avoid toxicity.
