Hepatitis B Surface Antigen

Test Code
HEPAS


Includes
Screen positive results will be sent to Quest Diagnostics for confirmation


Preferred Specimen
2 mL serum


Minimum Volume
1 mL


Other Acceptable Specimens
None


Instructions


None




Transport Container
Serum separator tube (SST)


Transport Temperature


Refrigerated (cool packs)




Specimen Stability
 Refrigerated: 5 days
Frozen: 3 months


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic


Methodology
Immunoassay (IA)

Setup Schedule
24/7


Report Available
Same day (unless screen is positive)


Limitations
Results obtained from immunosuppressed patients should be interpreted with caution. Patients receiving mouse antibody therapy may produce false-negative results.


Reference Range
Non-Reactive


Clinical Significance
Surface antigen usually appears in the serum after an incubation period of 1 to 6 months following exposure to Hepatitis B virus and peaks shortly after onset of symptoms. It typically disappears within 1 to 3 months. Persistence of Hepatitis B Surface Antigen for greater than 6 months is a prognostic indicator of chronic Hepatitis B infection.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.