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Lactate Dehydrogenase (LD)
Test CodeLDH
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Other Acceptable Specimens
Heparinized plasma
Instructions
None
Transport Container
Serum separator tube (SST)
Transport Temperature
Ambient
Specimen Stability
Refrigerated: 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Received frozen • Anticoagulants other than heparin
Methodology
Spectrophotometry (SP)
Setup Schedule
24/7
Report Available
Same day
Reference Range
100-225 U/L
Clinical Significance
Elevations in serum lactate dehydrogenase occur from myocardial infarction, liver disease, pernicious and megaloblastic anemia, pulmonary emboli, malignancies, and muscular dystrophy. Since lactic dehydrogenase is present in many body tissues, it's diagnosis usefulness is limited. Tissue specificity may be enhanced by isoenzyme analysis.