THYROSEQ

Test Code

THYROSEQ

Includes

Reliable diagnosis of all types of thyroid nodules, including Hürthle cell nodules, medullary thyroid carcinoma, parathyroid, or other non-thyroidal lesions in a single workflow

Preferred Specimen

TISSUE SAMPLE OF THYROID

Patient Preparation
ThyroSeq uses an innovative technology called Next Generation Sequencing to analyze genes important for cancer development. ThyroSeq uses cells already collected during your FNA procedure and sequences the hundreds of gene regions in one tube. Pathologists interpret genetic alterations found to determine the risk of cancer in your thyroid nodule. ThyroSeq results, when combined with your cytology diagnosis and thyroid nodule imaging, help your doctor personalize the management of your thyroid nodule.

Minimum Volume

FOLLOW PACKAGE DIRECTIONS WITHIN THE KIT

Instructions

COLLECTION INSTRUCTIONS ON THE BACK OF THE PROVIDED THYROSEQ REQUISITION AND BY REQUEST FROM THE CYTOLOGY DEPARTMENT. ***VIALS ARE LIGHT SENSITIVE*** STORE IN DARK BAG UNTIL USE* PRIOR TO ORDER ***MUST HAVE PERFORMED EITHER PRIOR THYROID CYTOLOGY, OR CONCURRENT THYROID CYTOLOGY. SEND TO CYTOLOGY ASAP
WITH THYROSEQ REQUISITION AND CYTOLOGY REQUISTION.

Transport Container

THYROSEQ KIT OBTAINED IN HISTOLOGY

Transport Temperature

FOLLOW PACKAGE RECOMMENDATIONS

Specimen Stability

IN LIGHT PROTECTIVE BAG UNTIL ORDER IS PLACED.

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

IMPROPER STORAGE
NOT IN LIGHT PROTECTED BAG

Methodology

Comprehensive genomic profiling of DNA and RNA to detect four main classes of molecular alterations 1,10
Inclusion of all markers of aggressive thyroid cancer (TERT, TP53, AKT1, PIK3CA, and others) 1,10
Unique and proprietary database of >3,000 thyroid nodules with known surgical outcome9

Clinical Significance

ThyroSeq was designed by expert physicians in the field of thyroid cancer and combines years of scientific and clinical experience to help you and your doctor personalize your care.

Performing Laboratory
CBL PATH
760 WESTCHESTER AVE.
RYEBROOK, NY 10573

Additional Information
Thyroseq

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.