FACTOR 5 LEIDEN MUTATION/PROTHROMBIN MUTATION(WH)

Message
CONTAINS TWO TEST IN A PANEL ONLY. FACTOR 5 LEIDEN MUTATION, AND PROTHROMBIN MUTATION. CAN NOT ORDER SEPARATELY.


Test Code
FACT 5 LEIDEN/FACT 2 MUT


Alias/See Also
FACTOR 2 MUTATION


Includes
FACTOR 5 LEIDEN MUTATION, AND PROTHROMBIN MUTATION.


Preferred Specimen
WHOLE BLOOD-LAV TOP TUBE REFRIGERATED


Minimum Volume
4ML


Instructions
Draw one LAVENDER (EDTA) top tube. Do not spin or freeze sample. Store whole blood sample in refrigerator.


Transport Container
ORIGINAL TUBE


Transport Temperature
REFRIGERATED


Methodology
CEPHEID-REAL TIME PCR-IVD

Setup Schedule
ONE RUN/WEEK- VARIABLE ON DAY


Report Available
8 DAYS


Reference Range
Homozygous Normal (Wild-Type)


Clinical Significance
The Factor II (Prothrombin) G20210A test is an in vitro diagnostic test for the detection and genotyping of the Factor II (Prothrombin) G20210A mutation as an aid to diagnosis in the evaluation of patients with suspected thrombophilia. Inherited thrombophilia predisposes an individual to thrombotic events such as venous thrombosis, the third most common cardiovascular disease . Activated protein C (APC) resistance is regarded as the most prevalent coagulation abnormality associated with venous thrombosis. Patients testing positive for APC resistance or the Factor V Leiden mutation should be considered for molecular genetic testing for the other most common thrombophilias with overlapping phenotype, for which testing is available at present [i.e., the Factor II (Prothrombin) G20210A variant] which is present in 1–2% of the general population and its involvement in venous thromboembolism is well established.


Performing Laboratory
PERFORMING LAB: WEST HAVEN Molecular Diagnostics Laboratory PHONE #: 203-932-5711 EXT: 2915/3556 FAX: 203-937-4786



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.