|
|
| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
BETA 2 MICROGLOBULIN (B)
MessageSEND OUT/BOSTON
Test Code
B2M
Alias/See Also
B2MG
Preferred Specimen
DRAW 1 RED TOP, CLOT, SPIN AND SEPARATE INTO TRANSFER TUBE, REFRIGERATE
FOR TRANSPORT.
FOR TRANSPORT.
Minimum Volume
2 MLS
Instructions
DRAW 1 RED TOP, CLOT, SPIN AND SEPARATE INTO TRANSFER TUBE, REFRIGERATE
FOR TRANSPORT.
FOR TRANSPORT.
Transport Container
PLASTIC TUBE
Transport Temperature
REFRIGERATED
Specimen Stability
Room temperature: 1 day
Refrigerated (2-8°C): 3 days
Frozen (-20°C or colder): 6 months
Refrigerated (2-8°C): 3 days
Frozen (-20°C or colder): 6 months
Methodology
Turbidimetric/Immunoturbidimetic
Setup Schedule
M-F
Report Available
1-2 DAYS
Reference Range
1.42 – 3.21 mg/L
Clinical Significance
Beta-2-microglobulin normally passes through the glomerulus into the proximal tubule where much of it is reabsorbed. Serum levels are therefore an index of glomerular function. When impaired, serum levels rise in inverse ratio to glomerular filtration rate. Increased amounts of beta-2-microglobulin are excreted in several renal disorders, e.g., Balkan nephropathy, heavy metal poisoning and renal tubular disease due to therapeutic agents. Serial levels of beta-2-microglobulin in serum and urine are used to evaluate transplant viability and anticipate rejection. Following a successful graft, serum levels decline toward normal. Increasing serum levels provide an early sign of rejection. Elevated levels are also noted in lymphproliferative disorders, neoplasms (malignant and benign), inflammatory disease, and autoimmune diseases such as systemic lupus erythematosus (SLE) and Sjögren's disease.
Performing Laboratory
Test performed at West Roxbury Chemistry Lab Contact: Jonathan Dryjowicz-Burek 857-203-5973
Additional Information
BETA 2 MICROGLOBULIN
