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ATHENA#813,MEN2(RET) DNA
MessageQUEST->ATHENA LABS
Test Code
ATHENA#813
CPT Codes
81406
Preferred Specimen
WHOLE BLOOD
Minimum Volume
8mLs
Instructions
******NEEDS PATHOLOGIST APPROVAL***** DRAW 2 EDTA LAV TOPS, SEND WHOLE BLOOD. REFRIGERATED TO LAB. SAMPLE IS SENT TO QUEST TC 900609 AND TRANSFERED TO ATHENA 813 SAMPLE IS STABLE FOR 10 DAYS REFRIGERATED. Higher blood volumes ensure adequate DNA quantity, which varies with WBC, specimen condition, and need for confirmatory testing. Patients, 0-3 years have higher WBC, yielding more DNA per mL of blood
Transport Container
ORIGINAL TUBES
Transport Temperature
REFRIGERATED
Specimen Stability
Room temperature: 10 days, Refrigerated: 10 days, Frozen: Unacceptable
Methodology
Sanger Sequencing
Report Available
14-28 DAYS
Reference Range
No mutation detected
Clinical Significance
Detects mutations in the coding sequence of RET
Typical Presentation: MEN2A and FMTC: Neck mass or pain, diarrhea, MEN2B: diarrhea or constipation, neuromas on distal surface of tongue, mucosal surface of upper eyelids, vermillion border of lips, marfanoid habitus
Indications for testing: Medullary thyroid cancer; Pheochromocytoma; Family history of MEN2
Typical Presentation: MEN2A and FMTC: Neck mass or pain, diarrhea, MEN2B: diarrhea or constipation, neuromas on distal surface of tongue, mucosal surface of upper eyelids, vermillion border of lips, marfanoid habitus
Indications for testing: Medullary thyroid cancer; Pheochromocytoma; Family history of MEN2
Performing Laboratory
ATHENA DIANOSTICS 200 Forest Street, 2nd Floor Marlborough, MA 01752 Phone (508) 756-2886
Additional Information
MEN2(RET) DNA SEQUENCING TEST
