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B 12 VIT VITAMIN B-12
MessageCHEMISTRY
Test Code
VB12
Alias/See Also
VITAMIN B12
Preferred Specimen
SERUM
Minimum Volume
1-2 MLS
Instructions
DRAW 1 GOLD TOP SST TUBE, LET CLOT, SPIN, SEND TO LAB REFRIGERATED.
Transport Container
ORIGINAL TUBE
Transport Temperature
REFRIGERATED
Specimen Stability
Room temperature: 3 days
Refrigerated (2-8°C): 7 days
Separate and freeze at -20°C or colder if not tested within 7 days.
Max freeze/thaw cycles: 3
Refrigerated (2-8°C): 7 days
Separate and freeze at -20°C or colder if not tested within 7 days.
Max freeze/thaw cycles: 3
Methodology
Chemiluminescence
Setup Schedule
DAILY
Report Available
DAILY
Reference Range
200 - 900 pg/mL
Levels above 300 or 400 pg/mL are rarely associated with B12 deficiency
induced hematological or neurological disease, respectively. Further
testing is suggested for SYMPTOMATIC patients with B12 level between 100
and 300 pg/mL (hematological abnormalities) and between 100 and 400 pg/mL
(neurological abnormalities).
Levels above 300 or 400 pg/mL are rarely associated with B12 deficiency
induced hematological or neurological disease, respectively. Further
testing is suggested for SYMPTOMATIC patients with B12 level between 100
and 300 pg/mL (hematological abnormalities) and between 100 and 400 pg/mL
(neurological abnormalities).
Clinical Significance
Vitamin B12 is decreased in pernicious anemia, total or partial gastrectomy, malabsorption and certain congenital and biochemical disorders.
Performing Laboratory
WHITE RIVER JUNCTION VA VT CHEMISTRY 802-295-9363 EXT: 5518, 5519
