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VITAMIN B-12
MessageCHEMISTRY
Test Code
VIT B12
Alias/See Also
VIT B12, VITB12, B12 VIT, B 12 VIT
Preferred Specimen
SERUM
Minimum Volume
2mLs
Instructions
DRAW 1 GOLD TOP SST TUBE, LET CLOT FOR 30 MINUTES AND SPIN DOWN.
Transport Container
ORIGINAL TUBE
Transport Temperature
REFRIGERATE
Specimen Stability
Room temperature: 3 days
Refrigerated (2-8°C): 7 days
Separate and freeze at -20°C or colder if not tested within 7 days.
Max freeze/thaw cycles: 3
Refrigerated (2-8°C): 7 days
Separate and freeze at -20°C or colder if not tested within 7 days.
Max freeze/thaw cycles: 3
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
HEMOLYSIS
Methodology
Chemiluminescence
Setup Schedule
DAILY
Report Available
DAILY
Reference Range
200 - 900 pg/mL
Levels above 300 or 400 pg/mL are rarely associated with B12 deficiency
induced hematological or neurological disease, respectively. Further
testing is suggested for SYMPTOMATIC patients with B12 level between 100
and 300 pg/mL (hematological abnormalities) and between 100 and 400 pg/mL
(neurological abnormalities).
Levels above 300 or 400 pg/mL are rarely associated with B12 deficiency
induced hematological or neurological disease, respectively. Further
testing is suggested for SYMPTOMATIC patients with B12 level between 100
and 300 pg/mL (hematological abnormalities) and between 100 and 400 pg/mL
(neurological abnormalities).
Clinical Significance
Vitamin B12 is decreased in pernicious anemia, total or partial gastrectomy, malabsorption and certain congenital and biochemical disorders.
Performing Laboratory
WHITE RIVER JUNCTION VT VA- CHEMISTRY 802-295-9363 ext: 5518, 5519
