A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

VANCOMYCIN, TROUGH

Message
CHEMISTRY


Test Code
VANCO TROUGH


Preferred Specimen
SERUM


Minimum Volume
2mLs


Instructions
DRAW 1 RED TOP TUBE, LET CLOT FOR 30 MINUTES, AND SPIN DOWN. TRANSFER SERUM INTO PLASTIC TRANSFER TUBE. Draw trough levels just prior to next dose at steady-state conditions (approximately after 4th dose).


Transport Container
PLASTIC TUBE


Transport Temperature
REFRIGERATED


Specimen Stability
Room temperature: 3 days. Separate if not tested within this time.
Refrigerated (2-8°C): 8 days
Frozen (-20°C or colder): 3 months


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Collected in gel tube


Methodology
Chemiluminescent microparticle immunoassay

Setup Schedule
DAILY


Report Available
DAILY


Reference Range
10-20 ug/ml
For COMPLICATED INFECTIONS such as bacteremia, endocarditis, meningitis and hospital acquired pneumonia caused by S. aureus, recommended TROUGH level is 15-20 ug/mL. For uncomplicated infections, troughs of 10-15 ug/mL may be adequate. Trough therapeutic range was increased to address evidence based guidelines for Vancomycin use aimed at improving efficacy of antibiotics for serious infections & reducing emergence of resistant strains.


Clinical Significance
Vancomycin is an antibiotic used in the treatment of serious bacterial infections, especially methicillin-resistant staphylococci. Vancomycin is also used in treatment for penicillin-allergic patients who cannot receive or have failed to respond to other drugs, including the penicillins and/or cephalosporins and for other infections caused by vancomycin-susceptible organisms.


Performing Laboratory
WHITE RIVER JUNCTION VT VA- CHEMISTRY 802-295-9363 EXT: 5518, 5519



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.