LAMBDA-KAPPA LIGHT CHAIN SERUM(B)

Message

SENDOUT/BOSTON

Test Code

LAMBDA-KAPPA LIGHT CHAIN SERUM

Alias/See Also

FREE KAPPA/LAMBDA LIGHT-CHAIN SERUM, LAMBDA-KAPPA LIGHT CHAIN SERUM, LIGHT CHAIN FREE KAPPA/LAMBDA

Includes

KAPPA LC FREE
LAMBDA LC FREE
FREE K/L RATIO

Preferred Specimen

SERUM: GOLD TOP TUBE

Minimum Volume

2mLs

Instructions

DRAW 1 GOLD TOP SST TUBE, LET CLOT FOR 30 MINUTES, SPIN DOWN, AND SEND TO LAB.

Transport Container

ORIGINAL TUBE

Transport Temperature

REFRIGERATED

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Reject if 3+ or 4+ lipemia/icterus/hemolysis

Methodology
Optilite/Colorimetric

Setup Schedule

M-F

Report Available

TAT 2-5 DAYS

Reference Range

Ratio 0.26 to 1.65
Free Kappa 3.30-22.50 mg/L
Free Lambda 5.71-30.50 mg/L

Clinical Significance

Elevated serum levels of monoclonal free light chains with abnormal free kappa/free lambda ratios is associated with malignant plasma cell disorders including multiple myeloma, nonsecretory multiple myeloma, light chain disease, and primary amyloidosis. This assay may also be useful in monitoring the treatment of patients previously diagnosed with multiple myeloma.

High or low ratios are suggestive of monoclonal gammopathies.

Performing Laboratory
Test performed in the West Roxbury Immunology Lab Contact: Cassandra Mota, 857-203-5941

Additional Information
KAPPA/LAMBDA LIGHT CHAIN SERUM

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.