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Smooth Muscle Antibody with Reflex to Titer
Test Code263
Alias/See Also
LAB304669
Includes
If Smooth Muscle Antibody Screen is positive, then Smooth Muscle Antibody Titer will be performed at an additional charge (CPT code(s): 86015).
Preferred Specimen
0.5 mL serum
Minimum Volume
0.1 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic
Methodology
Immunofluorescent Assay (IFA)
Setup Schedule
Set up: Mon, Tues, Thurs-Sat; Report available: 3-4 days
Clinical Significance
Smooth muscle antibodies are detected in 85% of patients with chronic active hepatitis and in less than 50% of patients with primary biliary cirrhosis. Smooth muscle antibodies are usually negative in extrahepatic biliary obstruction, drug induced liver disease, viral hepatitis and hepatoma.
