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Arbovirus Antibodies (IgG, IgM), IFA, Serum
Test Code34980
Alias/See Also
LAB1237154
Includes
California Encephalitis (IgG, IgM), Eastern Equine Encephalitis (IgG, IgM), St. Louis Encephalitis (IgG, IgM), Western Equine Encephalitis (IgG, IgM)
Preferred Specimen
1 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.2 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Icteric • Lipemic samples
Methodology
Immunofluorescence Assay (IFA)
Setup Schedule
Monday-Friday Morning
Report available: 3 Days
Report available: 3 Days
Limitations
False-positive results may be produced if the patient has been immunized against yellow fever or if the patient has had previous infections that produce similar, cross-reacting antibodies.
Clinical Significance
Serum is tested against antigens of California Encephalitis (La Crosse), Eastern Equine Encephalitis, St. Louis Encephalitis and Western Equine Encephalitis viruses. IgG titers >=1:16 suggest exposure, while the presence of IgM indicates recent infection. Incidence is seasonal from mid- to late-summer (July-October).
