ACUTE MYELOID LEUKEMIA (AML)/MYELODYSPLASTIC SYNDROME (MDS), FISH

Test Code

LAB1238014

Preferred Specimen

Bone Marrow: 0.5-1 mL aspirate in dark green top tube (sodium heparin)

Minimum Volume

Bone Marrow: 0.5mL aspirate (sodium heparin)

Other Acceptable Specimens

Blood: 2-3 mLwhole blood in a dark green top tube (sodium heparin)
[BONE MARROW PREFERRED] Lavender top (EDTA) acceptable for FISH only (no karyotype ordered) samples.

Instructions

Place in cytogenetics bucket near chemistry.

Transport Temperature

Ambient or refrigerated (prolonged transport conditions) NOT FROZEN

Specimen Stability

Bone Marrow: Ambient (preferred), Refrigerated (accepted)

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Insufficient or clotted sample, more than 4 days old when received in laboratory.

Methodology
Fluorescent In Situ Hybridization (FISH), (Panel includes the following probes: PDGFRA, PDGFRB, JAK2, BCR/ABL, CBFB, FGFR1)

Setup Schedule

Samples processed Monday through Saturday.

Report Available

Results reported Monday through Friday

Performing Laboratory
West Virginia University Hospital, Inc.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.