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PROTEINASE 3 ANTIBODIES, IGG, SERUM
Test CodeLAB1459
Includes
If test result is positive, a sample will be sent for Cytoplasmic Neutrophil Antibodies testing.
Preferred Specimen
Gold Top Tube
Pediatric: 2 Gold top Microtainers
Pediatric: 2 Gold top Microtainers
Minimum Volume
Required for Testing: 0.5 mL
Other Acceptable Specimens
Red Top Tube
Instructions
Centrifuge within 1 hour of collection. Separate serum from cells if Red Top Tube. Aliquot 0.5 mL serum.
Transport Temperature
Refrigerated
Specimen Stability
Refrigerated: 2-8°C 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Failure to fully fill tube.
Methodology
Multiplex Immunoassay
Setup Schedule
Monday - Friday, Dayshift
Clinical Significance
Evaluating patients suspected of having Wegener granulomatosis (WG)
Distinguishing between WG and other forms of vasculitis, inconjunction with Myeloperoxidase IgG Antibodies and ANCA/ Cytoplasmic Neutrophil Antibodies
May be useful to follow treatment response or to monitor disease activity in patients with myeloperoxidase antibodies
If test result is positive or equivocal, a sample will be sent for Cytoplasmic Neutrophil Antibodies testing.
Distinguishing between WG and other forms of vasculitis, inconjunction with Myeloperoxidase IgG Antibodies and ANCA/ Cytoplasmic Neutrophil Antibodies
May be useful to follow treatment response or to monitor disease activity in patients with myeloperoxidase antibodies
If test result is positive or equivocal, a sample will be sent for Cytoplasmic Neutrophil Antibodies testing.
Performing Laboratory
West Virginia University Hospital, Inc.
