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IMMATURE PLATELET FRACTION (IPF)
Test CodeLAB1231001
Preferred Specimen
One 3mL lavender top tube
Pediatric Volume: One lavender top microtainer (0.5mL blood)
Pediatric Volume: One lavender top microtainer (0.5mL blood)
Minimum Volume
1mL blood(Adult)
Transport Container
T
Transport Temperature
Refrigerated
Specimen Stability
Ambient: 24 hours Refrigerated: 48 hours
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Clotted specimen, platelet clumps seen on stained slide, or questionable specimen integrity due to improper collection.
Methodology
Sysmex XN10 (fluorescence assay)
Setup Schedule
Sunday-Saturday
Clinical Significance
The IPF measures the most immature platelet forms with high nucleic acid content. IPF results may be used to evaluate thrombocytopenic
patients caused by peripheral destruction or insufficient marrow production of platelets. Additionally, IPF may be used to evaluate
platelet production in patients receiving chemotherapy and/or platelet engraftment in hematopoietic stem cell transplant recipients.
An elevated IPF suggests that platelets are being formed, which can mitigate the need for platelet transfusion depending on the clinical
situation.
patients caused by peripheral destruction or insufficient marrow production of platelets. Additionally, IPF may be used to evaluate
platelet production in patients receiving chemotherapy and/or platelet engraftment in hematopoietic stem cell transplant recipients.
An elevated IPF suggests that platelets are being formed, which can mitigate the need for platelet transfusion depending on the clinical
situation.
Performing Laboratory
West Virginia University Hospital, Inc.
Berkeley Medical Center
Barnesville Hospital
Garrett Regional Medical Center
Jefferson Medical Center
Summersville Regional Medical Center
St. Joseph’s Hospital
United Hospital Center
Uniontown Hospital
