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Histoplasma Antibody, Complement Fixation, CSF
Test Code5297
Alias/See Also
LAB1268
Includes
Yeast Phase Antibody and Mycelial Phase Antibody
Preferred Specimen
1 mL CSF collected in a sterile, leak-proof container
Minimum Volume
0.5 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly icteric
Methodology
Complement Fixation (CF)
Setup Schedule
Set up: Tues-Sat; Report available: 3-6 days
Clinical Significance
Central nervous system infection occurs in up to 25% of patients with subacute progressive disseminated histoplasmosis. Detection of antibodies in CSF can serve as a useful tool for identifying these patients.

