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Arbovirus Antibody Panel, IFA (CSF) [3621X]
Test Code18344
Alias/See Also
LAB1655
Includes
California Encephalitis (IgG, IgM), Eastern Equine Encephalitis (IgG, IgM), St. Louis Encephalitis (IgG, IgM), Western Equine Encephalitis (IgG, IgM)
Preferred Specimen
1 mL CSF submitted in a sterile, leak-proof container
Minimum Volume
0.5 mL
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 5 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Methodology
Immunofluorescence Assay (IFA)
Setup Schedule
Set up: Mon-Fri; Report available: 6 days
Limitations
False-positive results may be produced if the patient has been immunized against yellow fever or if the patient has had previous infections that produce similar, cross-reacting antibodies.
Clinical Significance
Arboviruses are classically defined as viruses that can be transmitted to humans by an arthropod vector. Arboviral diseases of humans may present with four manifestations: fever, encephalitis, hemorrhagic fever and polyarthritis. Fever is the most common sign and is usually benign, mild and undifferentiated, lasting 3-7 days. This panel includes of the following arboviruses that infect the central nervous system: St. Louis encephalitis, California encephalitis and Eastern and Western Equine encephalitis.
