THYROGLOBULIN ANTIGEN w/ANTIBODY SCREEN

Test Code

LAB8192

CPT Codes
86800, 84432

Preferred Specimen

1 Gold tube (SST)

Minimum Volume

1.5 mL (3 mL optimal)

Other Acceptable Specimens

1 Green tube (Lithium Heparin)

Instructions

Centrifuge for complete separation of serum or plasma from red cells WITHIN 2 HOURS of collection. Refrigerate until tested.

Transport Container

Transfer tube

Transport Temperature

Refrigerate

Specimen Stability

2-8°C up to 7 days; otherwise freeze at -20°C or lower

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

EDTA or K2EDTA plasma
Quantity not sufficient

Methodology
Chemiluminescent Immunoassay or LCMS

Setup Schedule

M, T, W, Th, F, Sa, Su

As received

Report Available

Within 24 hours of receipt

Reference Range

Thyroglobulin Antibody (0 - 4 IU/mL)
Thyroglobulin Antigen (0.0 - 34.9 ng/mL)

Thyroglobulin by LCMS Reference Range
Age	Value (ng/mL)
6 months - 3 years	7.4 - 48.7
4 - 7 years	4.1 - 40.5
8 - 17 years	0.8 - 29.4
18 years and older	1.3 - 31.8

Note: Samples that are negative for Thyroglobulin antibodies will be referred to Thyroglobulin Ag by Immunoassay.

Samples that are positive for Thyroglobulin antibodies will be referredt to Thyroglobulin by LC-MS

Clinical Significance

Intended to aid in monitoring for the presence of local or metastatic thyroid tissue in patients who have had thyroid gland ablation and who lack serum thyroglobulin antibodies. The presence of serum autoantibodies to thyroglobulin can interfere with immunoassays for thyroglobulin.

Performing Laboratory
Alverno Central Lab (if reflexed, ARUP)

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.