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RPR MONITORING
MessageNote: This test is useful for determining the current disease status and evaluating the response to therapy for KNOWN Syphilis patients. This test should NOT be used as a primary diagnostics assay for Syphilis.
Test Code
LAB7941
CPT Codes
86592, 86593 (reflex)
Includes
- RPR
- RPR titer (if positive)
Preferred Specimen
1 Gold tube (SST)
Minimum Volume
0.5 mL (1 mL optimal)
Other Acceptable Specimens
1 Green tube (Lithium Heparin)
OR
OR
Instructions
Centrifuge for complete separation of serum or plasma from red cells.
Transport Container
Transfer tube
Transport Temperature
Refrigerate
Specimen Stability
2-8°C up to 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis
Methodology
Multiplex Flow Immunoassay
Setup Schedule
M, T, W, Th, F, Sa, Su
Batched; once per day
Batched; once per day
Report Available
Same day received
Reference Range
Non-Reactive
Reactive and Equivocal results are reported to the Illinois Board of Health. Please note the physician has a separate reporting requirement independent from the laboratory.
Treatment response is generally indicated by a 4-fold reduction in RPR Titer. Patients with primary or secondary Syphilis should be re-examined clinically and serologically at 6 months and again at 12 months following treatment. RPR Titers typically decrease following successful treatment, but this may occur over a period of months to years.
Assay interference resulting in false positive results may occur due to cross-reacting antibodies from patients diagnosed with Systemic Lupus Erythemaotosus (SLE), pregnancy, malaria, autoimmune disease, viral pneumonia, intravenous drug use, and in people who have been recently immunized.
Reactive and Equivocal results are reported to the Illinois Board of Health. Please note the physician has a separate reporting requirement independent from the laboratory.
Treatment response is generally indicated by a 4-fold reduction in RPR Titer. Patients with primary or secondary Syphilis should be re-examined clinically and serologically at 6 months and again at 12 months following treatment. RPR Titers typically decrease following successful treatment, but this may occur over a period of months to years.
Assay interference resulting in false positive results may occur due to cross-reacting antibodies from patients diagnosed with Systemic Lupus Erythemaotosus (SLE), pregnancy, malaria, autoimmune disease, viral pneumonia, intravenous drug use, and in people who have been recently immunized.
Performing Laboratory
Alverno Central Lab
