A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

RIBONUCLEOPROTEIN ANTIBODY

Test Code
LAB8415 (MISCELLANEOUS)


Alias/See Also
  • nRNP
  • U1RNP


CPT Codes
86235

Preferred Specimen
1 Gold tube (SST)


Minimum Volume
0.5 mL (1 mL optimal)


Other Acceptable Specimens
1 Lavender tube (EDTA)


OR

1 Green tube (Lithium Heparin)


OR



Instructions
Centrifuge for complete separation of serum or plasma from red cells. 


Transport Container
Transfer tube


Transport Temperature
Refrigerate


Specimen Stability
  • 2-8°C up to 7 days
  • otherwise freeze at -20° or lower


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
  • Hemolysis
  • Lipemia


Methodology
Multiplex Flow Immunoassay

Setup Schedule
M, T, W, Th, F, Sa, Su

Batched; once per day


Clinical Significance
RNP is 1 of 4 autoantigens commonly referred to as extractable nuclear antigens (ENA). The other ENAs are SS-A/Ro, SS-B/La, and Sm. Each ENA is composed of 1 or more proteins associated with small nuclear RNA species (snRNP) ranging in size from 80 to approximately 350 nucleotides. Antibodies to ENAs are common in patients with connective tissue diseases (systemic rheumatic diseases) including LE, MCTD, Sjogren syndrome, scleroderma (systemic sclerosis), and polymyositis/dermatomyositis.


Performing Laboratory
Alverno Central Lab



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.