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| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
FREE KAPPA AND LAMBDA LIGHT CHAINS, SERUM
Test CodeLAB8030
CPT Codes
83520 x2
Includes
- Free Kappa
- Free Lambda
- Free Kappa/Labmda ratio
- Pathologist Interpretation
Preferred Specimen
1 Gold tube (SST)
Note: Plasma samples not acceptable
Note: Plasma samples not acceptable
Patient Preparation
None
Minimum Volume
1 mL (5 mL optimal)
Other Acceptable Specimens
1 Red tube
Instructions
Centrifuge for complete separation of serum from red cells ASAP or WITHIN 2 HOURS of collection. Refrigerate until tested.
Transport Container
Transfer/aliquot tube
Transport Temperature
Refrigerated
Specimen Stability
- 15-30°C up to 2 hours
- 2-8°C up to 7 days
- Frozen at -20° C: 2 weeks
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
- Plasma samples
- Room temperature samples
Methodology
Quantitative turbdimetry
Setup Schedule
M, T, W, Th, F
Report Available
1-3 days
Reference Range
Kappa: 3.30 - 19.40 mg/L
Lambda: 5.70 - 26.30 mg/L
Lambda: 5.70 - 26.30 mg/L
| Components | Reference Interval |
|---|---|
| Lambda Quantitative Free Light Chains, Serum | 0.57 - 2.63 mg/dL |
| Kappa Quantitative Free Light Chains, Serum | 0.33 - 1.94 mg/dL |
| Kappa/Lambda Free Light Chain Ratio, Serum | 0.26 - 1.65 |
Clinical Significance
Aids in the evaluation and management of multiple myeloma and related plasma cell disorders.
Note: This assay is highly sensitive to increasiing concentrations of monoclonal free kappa and free lambda light chains in serum of patinets with evolving or relapsing myelomas.
Note: This assay is highly sensitive to increasiing concentrations of monoclonal free kappa and free lambda light chains in serum of patinets with evolving or relapsing myelomas.
Performing Laboratory
Alverno Central Lab
