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INTERLEUKIN 6
Test CodeLAB8415 (MISCELLANEOUS)
Alias/See Also
- IL-6
- Cytokine
CPT Codes
83520
Preferred Specimen
1 Gold tube (SST)
Patient Preparation
None
Minimum Volume
0.5 mL (2 mL optimal)
Other Acceptable Specimens
1 Red tube
Instructions
Centrifuge for complete separation of serum from red cells WITHIN 2 HOURS of collection. Transfer serum to an aliquot or transfer tube.
Transport Container
Transfer/aliquot tube
Transport Temperature
Refrigerate
Specimen Stability
2-8°C up to 3 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
- Grossly lipemic
- Grossly Hemolyzed
Methodology
EIA
Setup Schedule
M, T, W, Th, F, Sa, Sun
As received
As received
Report Available
Within 48 hours of receipt
Reference Range
0.0-6.0 pg/mL
Clinical Significance
Interleukin-6 (IL-6) is a non-specific cytokine associated with an inflammatory response. It may be used in the evaluation of patients with suspected systemic infections, localized infections, and chronic inflammatory disorders including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), ankylosing spondylitis (AS), or inflammatory bowel disease (IBD). IL-6 increases may also be seen in patient with diabetes, cardiovascular disease, stroke, and some cancers. IL-6 concentrations appear to correlate with the severity of sepsis and appeear to be associated with more localized infections including prosthetic joint infections. With the recent emergence of SARS-CoV-2 (COVID-19), studies have shown elevated IL-6 levels correspond to progressing respiratory failure. Elevated concentrations of IL-6 must be interpreted in the context of the clinical scenario.
Performing Laboratory
Alverno Central Lab
