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HERPES SIMPLEX VIRUS 1/2 IGG ANTIBODY, WITH TITER
Test CodeLAB8415 (MISCELLANEOUS)
Alias/See Also
- HSV Glycoprotein G
CPT Codes
86695, 86696
Includes
- Herpes simplex I, IgG
- Herpes simplex II, IgG
Preferred Specimen
1 Gold tube (SST)
Patient Preparation
None
Minimum Volume
0.5 mL (1 mL optimal)
Other Acceptable Specimens
1 Red tube
Instructions
Centrifuge for complete separation of serum from red cells. Refrigerate until tested.
Transport Container
Gold tube
Transport Temperature
Refrigerate
Specimen Stability
- 2-8°C up to 2 days
- otherwise freeze at -20° or lower
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
- Hemolyzed
- Lipemic
Methodology
Multiplex Flow Immunoassay
Setup Schedule
M, T, W, Th, F, Sa, Sun
Batched; once per day run
Batched; once per day run
Reference Range
Negative: <0.9
Indeterminate: 0.9 - 1.0
Positive: ≥1.1
This assay is type-specific and will differentiate between HSV 1 and HSV 2 infections. A single positive result only indicates previous immunologic exposure. The performance of this assay has not been established for pediatric populations, for neonatal screening, or for the testing of immunocompromised patients. Levels early in the course of infection may not have detectable levels of HSV IgG. Test cannot differentiate between recent and old infections.
Indeterminate: 0.9 - 1.0
Positive: ≥1.1
This assay is type-specific and will differentiate between HSV 1 and HSV 2 infections. A single positive result only indicates previous immunologic exposure. The performance of this assay has not been established for pediatric populations, for neonatal screening, or for the testing of immunocompromised patients. Levels early in the course of infection may not have detectable levels of HSV IgG. Test cannot differentiate between recent and old infections.
Clinical Significance
HSV Type 1 is associated with lesions above the waist; HSV Type 2 is sexually transmitted and is a cause of generalized infections of the newborn. Also useful in undiagnosed congenital diseases and etiology of prolonged fever in immunosupressed patients.
Performing Laboratory
Alverno Central Lab
