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CHROMATIN
Test CodeLAB8415 (MISCELLANEOUS)
Alias/See Also
- Anti-Chromatin
- Anti-DNP
- Anti-Nucleosome
- Chromatin IgG Ab
CPT Codes
86235
Preferred Specimen
1 Gold tube (SST)

Patient Preparation
None
Minimum Volume
0.5 mL (1 mL optimal)
Other Acceptable Specimens
1 Lavender tube (EDTA)

OR
1 Green tube (Lithium Heparin)

OR
1 Green tube (Lithium Heparin)
Instructions
Centrifuge for complete separation of serum or plasma from red cells. Refrigerate until tested.
Transport Container
Gold tube
Transport Temperature
Refrigerate
Specimen Stability
- 2-8°C up to 7 days
- otherwise freeze at -20° or lower
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
- Hemolyzed
- Lipemic
Methodology
Multiplex Flow Immunoassay
Setup Schedule
M, T, W, Th, F, Sa, Su
Batched; once per day
Batched; once per day
Clinical Significance
Chromtain Antibody plays a central role in the autoimmune response in systemic lupus erythematosus (SLE). Approximately 90% of patients with SLE have sera that will exhibit reactivity to nucleosomes.
Performing Laboratory
Alverno Central Lab