CELIAC DISEASE PANEL, INFANT

Message

Note: This test should be ordered for patients <2 years old.

Test Code

LAB8259

CPT Codes
82784, 83516 x2 plus 86255 (if IgA is normal)

Includes

Total IgA
Tissue Transglutaminase IgA
Endomysial IgA antibody
Deamidated Gliadin IgA
Pathologist interpretation

Note: If the Total IgA result is low, Tissue Transglutaminase IgG and deamidated Gliadin IgG will be performed in place of Tissue Transglutaminase IgA, Endomysial IgA antibody and Deamidated Gliadin IgA.

Preferred Specimen

1 Gold tube (SST)

Patient Preparation
None

Minimum Volume

1 mL (5 mL optimal)

Instructions

Centrifuge for complete separation of serum from red cells. Refrigerate or freeze WITHIN 2 HOURS of collection time.

Transport Container

Gold tube

Transport Temperature

Refrigerate

Specimen Stability

2-8°C up to 2 days
otherwise freeze at -20° or lower

Methodology
ELISA

Setup Schedule

T, Th

Batched; Day shift only

Reference Range

IgA levels are normal and both TTG IgA and EMA IgA levels are within normal limits.

In low risk patients (<5% disease probability), celiac disease is effectively excluded.
In high risk patients (>5% disease probability), small bowel biopsy is recommended.

If histology is negative, celiac disease is excluded. If histology is positive, HLADQ2 and DQ8 testing is recommended.

Note: consider other causes for villous atrophy.

Clinical Significance

This panel of serologic studies facilitates the diagnosis of celiac disease and follows the recommendations of the American Gastroenterological Association (AGA).

Performing Laboratory
Alverno Central Lab

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.