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| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
CARDIOLIPIN ANTIBODY, IGA
Test CodeLAB7872
CPT Codes
86147
Includes
IgA
Preferred Specimen
Gold tube (SST)
Patient Preparation
None
Minimum Volume
1 mL
Other Acceptable Specimens
Green Tube (Lithium Heparin)
Instructions
Centrifuge for complete separation of serum or plasma from red cells.
Transport Container
Gold tube
Transport Temperature
Refrigerate
Specimen Stability
- 2-8°C up to 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolyzed samples will be rejected
Methodology
Multiplex Flow Immunoassay
Setup Schedule
M, T, W, Th, F, Sa, Su
Report Available
Result available within 24 hours of receipt
Reference Range
<20 GPL'U/mL is Negative
> or = to 20 GPL'U/mL is Positive
> or = to 20 GPL'U/mL is Positive
Clinical Significance
Preferred second-line testing for strong suspicion of seronegative antiphospholipid syndrome (APS). Order incrementally or concurrently with other non-criteria antiphospholipid antibody tests. Cardiolipin antibody IgG and IgM panel is preferred (CAGM2).
When a normal anti-cardiolipin antibody level is found in the presence of clinical manifestations, the lupus anticoagulant test should be performed. Patients with current or prior syphilis infections may have an elevated result without increased risk of thrombosis. Anti-cardiolipin antibodies can appear transiently at low levels during many infections. If a patient's result is increased while there are clinical signs of infection, the test should be repeated after an interval of six months.
When a normal anti-cardiolipin antibody level is found in the presence of clinical manifestations, the lupus anticoagulant test should be performed. Patients with current or prior syphilis infections may have an elevated result without increased risk of thrombosis. Anti-cardiolipin antibodies can appear transiently at low levels during many infections. If a patient's result is increased while there are clinical signs of infection, the test should be repeated after an interval of six months.
Performing Laboratory
Alverno Central Lab
