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| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
BETA-2-GLYCOPROTEINS, IGG/IGM
Test CodeLAB8050
CPT Codes
86146 x2
Includes
- Beta-2 glycoprotein IgG
- Beta-2 glycoprotein IgM
Preferred Specimen
Gold Tube (SST)
Patient Preparation
None
Minimum Volume
1 mL
Other Acceptable Specimens
Green Tube (Lithium Heparin)
Instructions
Allow gold tube to clot at room temperature then centrifuge for complete separation of serum from red cells.
Transport Container
Gold tube
Transport Temperature
Refrigerate
Specimen Stability
2-8°C up to 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis
Methodology
Multiplex Flow Immunoassay
Setup Schedule
M, T, W, Th, F, Sa, Su
Report Available
Within 24 hours of receipt
Reference Range
| Component | Range |
|---|---|
| IgG | <20.0 U/mL |
| IgM | <20 U/mL |
Clinical Significance
Acceptable initial test when antiphospholipid syndrome (APS) is strongly suspected. May also be useful in estimating risk of thrombosis and/or pregnancy-related morbidity in patients with SLE.
Presence of moderate to high levels of B2GP1 IgG and or IgM antibodies (>40 U/mL) on two or more occasions at least 12 weeks apart is a laboratory criterion for the diagnosis of antiphospholipid syndrome (APS). International reference materials and consensus of units for B2GP1 antibodies have not been established. Strong clinical correlation is recommended for a diagnosis of APS.
Presence of moderate to high levels of B2GP1 IgG and or IgM antibodies (>40 U/mL) on two or more occasions at least 12 weeks apart is a laboratory criterion for the diagnosis of antiphospholipid syndrome (APS). International reference materials and consensus of units for B2GP1 antibodies have not been established. Strong clinical correlation is recommended for a diagnosis of APS.
Performing Laboratory
Alverno Central Lab
