CREATININE CLEARANCE

Test Code

CRECL (OE), CRCL (LAB)

CPT Codes
82575

Includes

Height, Weight, BSA (Body Surface Area)
Total Volume
Serum Creatinine
Urine creatinine
Creatinine clearence

Preferred Specimen

1 Gold tube (SST)

AND

24 hour urine container without preservative

Patient Preparation
Avoid alcoholic beverages. Follow instructions on collecting a 24 hour collection (see below)

Minimum Volume

10 mL urine aliquot (20 mL urine aliquot optimal)
0.5 mL serum (1 mL serum optimal)

Other Acceptable Specimens

1 Green tube (Lithium Heparin)

AND

24 hour urine container without preservative

Instructions

Please provide patient height and weight. If sending aliquot of sample, MUST include total volume.

Mix the urine specimen well and measure the 24-hour volume
RECORD THE TOTAL VOLUME
Aliquot 20 mL of urine into urine tube or sterile container
Centrifuge blood tube(s) for complete separation of serum or plasma from red cells
If whole blood was collected, aliquot plasma
Refrigerate both urine and serum or plamsa specimens until tested.

Transport Container

Gold tube & Transfer tube

Transport Temperature

Refrigerate

Specimen Stability

2-8°C up to 4 days

Methodology
Enzymatic Rate

Setup Schedule

M, T, W, Th, F, Sa, Sun

As received; STAT testing not available

Report Available

Same day received

Reference Range

Creatinine Urine 24hr	0.7-1.6 G/24 hr
Creatinine	0.6-1.2 mg/dL
Creatinine Clearance	71-151 mL/min
eGFR Non-African American	>60
eGFR African American	>60

Clinical Significance

Creatinine Clearance is used to evaluate the glomerular filtration rate (GFR). Clearance is defined as that volume of plasma from which a measured amount of substance could be completely eliminated into the urine per unit of time.

Performing Laboratory
Alverno Central Lab

Additional Information
24 hour urine collection instructions

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.