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PLATELET ANTIBODY SCREEN
Test CodePLA
Alias/See Also
HLA Antibody Screening
CPT Codes
86022
Includes
Testing for antibodies against HPA-1a/b, HPA-2a/b, HPA-3a/b, HPA-4a, HPA-5a/b, GPIIb/IIIa, GPIa/IIa, GPIb/IX, GPIV and Class I HLA.
Preferred Specimen
Red Tube (No gel)

Minimum Volume
6mL
Transport Container
Seperate serum from red cells
Transport Temperature
Ship on wet ice. Freeze seperated serum if sample cannot be received in testing lab within 48 hours of collection (must be completely frozen and shipped on dry ice)
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Specimen drawn in wrong tube; grossly hemolyzed specimen; improperly labeled; quantity not sufficient for analysis .
Report Available
7 days
Limitations
No one test method is capable of detecting all unexpected antibodies to platelets. No antibody identification available with this test. Crossmatched platelets do not prevent transfusion reactions. Crossmatched platelet units should be irradiated prior to transfusion.
Reference Range
Negative
Clinical Significance
For diagnosis of supspected: Neonatal alloimmune thrombocytopenia (NAIT), Post-transfusion purpura (PTP), Autoimmune thrombocyotopenic purpura (AITP), Platelet refractoriness, Drug-induced thrombocytopenia
Performing Laboratory
American Red Cross