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Enterovirus Culture
Test Code2647
CPT Codes
87254
Includes
For respiratory samples please consider using the following offerings:
Enterovirus/Parechovirus RNA, Qualitative Real-Time PCR
Enterovirus/Parechovirus RNA, Qualitative Real-Time PCR
Preferred Specimen
Vesicular or ulcerative lesions, rectal swab, stool swab or stool in V-C-M medium (green-cap) tube or other FDA approved equivalent viral transport media
Minimum Volume
1 mL or 1 swab
Other Acceptable Specimens
3 mL CSF in sterile screw cap container (no preservative)
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
VCM or equivalent
Room temperature: Unacceptable
Refrigerated: 4 days
Frozen -20° C: Unacceptable
Frozen -70° C: 30 days
Sterile Container (Unpreserved specimens)
Room temperature: Unacceptable
Refrigerated: 72 hours
Frozen: Unacceptable
Room temperature: Unacceptable
Refrigerated: 4 days
Frozen -20° C: Unacceptable
Frozen -70° C: 30 days
Sterile Container (Unpreserved specimens)
Room temperature: Unacceptable
Refrigerated: 72 hours
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Bacterial transport systems • Dry swab • Molecular transport systems • Specimens in formalin or other fixatives • Respiratory specimens including sputum • Whole blood • Bone marrow • Serum • Plasma • Wooden-shaft swabs • Calcium alginate swabs
Methodology
Centrifuge Enhanced Culture • Immunofluorescence Stain
Setup Schedule
Set up: Mon-Sat; Report Available: 5-7 days
Clinical Significance
Enteroviruses are among the most common viruses infecting humans and are associated with diverse clinical syndromes ranging from minor febrile illness to severe, potentially fatal conditions (e.g., aseptic meningitis, encephalitis, paralysis, myocarditis, and neonatal enteroviral sepsis) and could be linked with the development of some chronic diseases (e.g., type 1 diabetes and dilated cardiomyopathy). Each year, an estimated 10 to 15 million symptomatic enterovirus infections occur in the United States.