Maternal Cell Contamination Study, STR Analysis

Test Code

10262

CPT Codes
81265<br />

Preferred Specimen

5 mL whole blood collected in an EDTA (lavender-top) tube

Minimum Volume

3 mL

Other Acceptable Specimens

Whole blood collected in: ACD (yellow-top) tube or sodium heparin (green-top) tube

Instructions

Maternal cell contamination (MCC) is performed as part of our quality assurance program. MCC studies will be completed if indicated on associated cytogenetic samples. MCC is required for all molecular tests ordered on fetal samples.

This test is run in conjunction with either a fetal specimen (amniotic fluid, dissected chorionic villus (CVS) biopsy or products of conception) or a cord blood sample. The assay cannot be run until fetal cultures or DNA is ready.

Whole blood: Specimen stability is crucial. Store and ship ambient immediately. Do not freeze.

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 8 days
Refrigerated: 8 days
Frozen: Unacceptable

Methodology
Multiplex Polymerase Chain Reaction • Fragment Analysis by Capillary Electrophoresis

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Run in conjunction with fetal clinical assay; Report available: 1 week

Clinical Significance

Maternal Cell Contamination Study, STR Analysis, provides assurance that test results from fetal specimens are not influenced by contaminating maternal material. This test also allows for establishing the proper maternal-fetal relationship between specimens by using sophisticated analysis of 15 highly polymorphic STR loci.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.