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Fungitell® (1-3)-Beta-D-Glucan, BAL
Test Code12348
CPT Codes
87449<br> **This test is not available for New York patient testing**
Includes
This test is not available for New York patient testing.
Preferred Specimen
1 mL bronchoalveolar lavage collected in a sterile screw-cap container
Minimum Volume
0.5 mL
Instructions
Transfer specimen into a cryogenic vial (DNAse, RNAse, pyrogen-free) or glucan free tube. Do not submit glass tubes.
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 5 days
Frozen -20° C: Unacceptable
Frozen -70° C: 7 days
Refrigerated: 5 days
Frozen -20° C: Unacceptable
Frozen -70° C: 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Glass tubes • samples received at Room temperature
Methodology
Protease Zymogen-based Colorimetric Kinetic Assay
Setup Schedule
Sets up 7 days a week.
Clinical Significance
Invasive Fungal Infections (IFI) are increasing, especially among immunocompromised patients. Most pathogenic fungi have (1-3)-beta-D-glucan in their cell walls and minute quantities are sloughed into the bloodstream and appear in the serum in cases of IFI. Monitoring serum (1-3)-beta-D glucan for evidence of elevated and rising levels provides a convenient surrogate marker for IFI.