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Yo Antibody Screen with Reflex to Titer and Western Blot, CSF
Test Code90117
CPT Codes
86255
Includes
If Yo Antibody Screen, IFA, CSF is positive, then Yo Antibody, Western Blot, CSF will be performed at an additional charge (CPT code(s): 84181).
If Yo Antibody, Western Blot, CSF is positive, then Yo Antibody, Titer, CSF will be performed at an additional charge (CPT code(s): 86256).
If Yo Antibody, Western Blot, CSF is positive, then Yo Antibody, Titer, CSF will be performed at an additional charge (CPT code(s): 86256).
Preferred Specimen
0.8 mL CSF in a sterile screw cap container
Patient Preparation
Overnight fasting is preferred
Minimum Volume
0.5 mL
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 8 hours
Refrigerated: 7 days
Frozen: 6 months
Refrigerated: 7 days
Frozen: 6 months
Methodology
Immunofluorescence Assay (IFA)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
See individual assays
Clinical Significance
Purkinje Cell (Yo) antibody is found in approximately half of the patients with paraneoplastic cerebellar degeneration and is associated with ovarian, uterine, and small cell lung carcinomas and Hodgkin’s lymphoma.
