Unstable Hemoglobin

Test Code

29385

CPT Codes
83068

Preferred Specimen

8 mL whole blood collected in an EDTA (lavender-top) tube

Minimum Volume

3 mL

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 24 hours
Refrigerated: 7 days
Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Received room temperature • Received frozen

Methodology
Alcohol Precipitation

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

A.M. Sets up 7 days a week.

Report Available

Reports in 1 day.

Clinical Significance

Unstable hemoglobins result from mutations around the heme pocket as well as contact points between the individual globin subunits resulting in hemolytic anemia. Hemoglobins carrying these structural modifications may denature and precipitate when exposed to alcohol, such as isopropanol.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.