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TSH with HAMA Treatment
Test Code19537
CPT Codes
84443 (x2)
Includes
Ultrasensitive TSH with and without HAMA treatment
Preferred Specimen
2 mL serum collected in a red-top tube (no gel)
Patient Preparation
Specimen collection after fluorescein dye angiography should be delayed for at least 3 days. For patients on hemodialysis, specimen collection should be delayed for 2 weeks. According to the assay manufacturer Siemens: "Samples containing fluorescein can produce falsely depressed values when tested with the ADVIA Centaur TSH3 Ultra assay".
Minimum Volume
1.5 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Methodology
Immunoassay (IA)
Setup Schedule
A.M. Sets up 5 days a week.
Report Available
Reports in 2 to 3 days.
Clinical Significance
Precision in the estimation of TSH is crucial to the follow-up of subjects with thyroid disorders. The preincubation of samples to remove HAMA immunoglobulins provides a way to ensure that an otherwise unsuspected rise or drop in TSH concentration will not be interpreted as either a false positive or false negative.