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Thrombin-Antithrombin (TAT) Complex
Test Code10162
CPT Codes
83520
Preferred Specimen
1 mL frozen platelet-poor plasma collected in a 3.2% sodium citrate (light blue-top) tube
Minimum Volume
0.5 mL
Instructions
Platelet poor plasma: Centrifuge light blue-top tube for 15 minutes at approximately 1500g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcl). Freeze immediately and ship on dry ice.
Note on requisition if patient is on oral anticoagulant therapy.
Note on requisition if patient is on oral anticoagulant therapy.
Transport Temperature
Frozen
Specimen Stability
Room temperature: 4 hours
Refrigerated: 4 hours
Frozen: 30 days
Refrigerated: 4 hours
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Thawed plasma
Methodology
Enzyme Linked Immunosorbent Assay (ELISA)
Setup Schedule
P.M. Sets up 1 day a week.
Report Available
Reports in 3 days.
Clinical Significance
Thrombin-Antithrombin (TAT) Complex is a parameter of coagulation and fibrinolysis. The Thrombin-Antithrombin Complex keeps clotting in check. Deficiencies may aid in understanding hypercoagulable states. Elevated concentrations have been associated with vascular complications associated with diabetes.