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Steroid Panel, PCOS/CAH Differentiation
Test Code90426
CPT Codes
84403, 84402, 82626, 82157, 83498, 82634
Includes
Testosterone, Total, LC/MS/MS
Testosterone, Free
DHEA, Unconjugated
Androstenedione
17-Hydroxyprogesterone
11-Deoxycortisol
Testosterone, Free
DHEA, Unconjugated
Androstenedione
17-Hydroxyprogesterone
11-Deoxycortisol
Preferred Specimen
1 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.6 mL
Instructions
Collect specimen in a no additive red-top tube. Spin down immediately and pour off into a plastic transport tube.
Transport Temperature
Frozen
Specimen Stability
Room temperature: 6 hours
Refrigerated: 72 hours
Frozen: 30 days
Refrigerated: 72 hours
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Moderate hemolysis • Grossly lipemic • Grossly icteric • Serum Separator Tube (SST®) • Plasma
Methodology
Chromatography/Mass Spectrometry • Equilibrium Dialysis
Setup Schedule
Night
Clinical Significance
This panel is important in the differential diagnosis of PCOS vs. non-classical CAH in women with oligomenorrhea/amenorrhea and signs of androgen excess.
